R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syn...
R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma
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Author / Creator
Overman, Jeroen , Fontaine, Frank , Wylie-Sears, Jill , Moustaqil, Mehdi , Huang, Lan , Meurer, Marie , Chiang, Ivy Kim , Lesieur, Emmanuelle , Patel, Jatin , Zuegg, Johannes , Pasquier, Eddy , Sierecki, Emma , Gambin, Yann , Hamdan, Mohamed , Khosrotehrani, Kiarash , Andelfinger, Gregor , Bischoff, Joyce and Francois, Mathias
Publisher
England: eLife Sciences Publications Ltd
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Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Contents
Propranolol is an approved non-selective β-adrenergic blocker that is first line therapy for infantile hemangioma. Despite the clinical benefit of propranolol therapy in hemangioma, the mechanistic understanding of what drives this outcome is limited. Here, we report successful treatment of pericardial edema with propranolol in a patient with Hypot...
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Full title
R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_80e594bab40d4aa48162ff158539d697
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_80e594bab40d4aa48162ff158539d697
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.43026
