Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neurobl...
Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neuroblastoma
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Resistance of high-risk metastatic neuroblastoma (HR-NB) to high dose chemotherapy (HD-CT) raises a major therapeutic challenge in pediatric oncology. Patients are treated by maintenance CT. For some patients, an adjuvant retinoid therapy is proposed, such as the synthetic retinoid fenretinide (4-HPR), an apoptotic inducer. Recent studies demonstra...
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Full title
Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neuroblastoma
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TN_cdi_doaj_primary_oai_doaj_org_article_8124479e834a4c2aa101771e7ee28af8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8124479e834a4c2aa101771e7ee28af8
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/1471-2407-9-97
