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Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5

Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_813408e384164dd1b862a65a8683e056

Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5

About this item

Full title

Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5

Publisher

England: eLife Sciences Publications, Ltd

Journal title

eLife, 2018-08, Vol.7 (8, 2018)

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications, Ltd

More information

Scope and Contents

Contents

Hearing and balance involve the transduction of mechanical stimuli into electrical signals by deflection of bundles of stereocilia linked together by protocadherin 15 (PCDH15) and cadherin 23 'tip links'. PCDH15 transduces tip link tension into opening of a mechano-electrical transduction (MET) ion channel. PCDH15 also interacts with LHFPL5, a cand...

Alternative Titles

Full title

Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_813408e384164dd1b862a65a8683e056

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_813408e384164dd1b862a65a8683e056

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.38770

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