Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity
Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Most computational methods that infer somatic copy number alterations (SCNAs) from bulk sequencing of DNA analyse tumour samples individually. However, the sequencing of multiple tumour samples from a patient’s disease is an increasingly common practice. We introduce Refphase, an algorithm that leverages this multi-sampling approach to infer haplot...
Alternative Titles
Full title
Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_813504d2d9cb4d0b820b2c0d5e22969e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_813504d2d9cb4d0b820b2c0d5e22969e
Other Identifiers
ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1011379
