FAK activity in cancer‐associated fibroblasts is a prognostic marker and a druggable key metastatic...
FAK activity in cancer‐associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer
About this item
Full title
Author / Creator
Zaghdoudi, Sonia , Decaup, Emilie , Belhabib, Ismahane , Samain, Rémi , Cassant‐Sourdy, Stéphanie , Rochotte, Julia , Brunel, Alexia , Schlaepfer, David , Cros, Jérome , Neuzillet, Cindy , Strehaiano, Manon , Alard, Amandine , Tomasini, Richard , Rajeeve, Vinothini , Perraud, Aurélie , Mathonnet, Muriel , Pearce, Oliver MT , Martineau, Yvan , Pyronnet, Stéphane , Bousquet, Corinne and Jean, Christine
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Cancer‐associated fibroblasts (CAFs) are considered the most abundant type of stromal cells in pancreatic ductal adenocarcinoma (PDAC), playing a critical role in tumour progression and chemoresistance; however, a druggable target on CAFs has not yet been identified. Here we report that focal adhesion kinase (FAK) activity (evaluated based on 397 t...
Alternative Titles
Full title
FAK activity in cancer‐associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer
Authors, Artists and Contributors
Author / Creator
Decaup, Emilie
Belhabib, Ismahane
Samain, Rémi
Cassant‐Sourdy, Stéphanie
Rochotte, Julia
Brunel, Alexia
Schlaepfer, David
Cros, Jérome
Neuzillet, Cindy
Strehaiano, Manon
Alard, Amandine
Tomasini, Richard
Rajeeve, Vinothini
Perraud, Aurélie
Mathonnet, Muriel
Pearce, Oliver MT
Martineau, Yvan
Pyronnet, Stéphane
Bousquet, Corinne
Jean, Christine
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_813c0054a8534fda924f316a50f89572
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_813c0054a8534fda924f316a50f89572
Other Identifiers
ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.202012010
