Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear con...
Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation
About this item
Full title
Author / Creator
Scholler, Pauline , Nevoltris, Damien , de Bundel, Dimitri , Bossi, Simon , Moreno-Delgado, David , Rovira, Xavier , Møller, Thor C. , El Moustaine, Driss , Mathieu, Michaël , Blanc, Emilie , McLean, Heather , Dupuis, Elodie , Mathis, Gérard , Trinquet, Eric , Daniel, Hervé , Valjent, Emmanuel , Baty, Daniel , Chames, Patrick , Rondard, Philippe and Pin, Jean-Philippe
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Antibodies have enormous therapeutic and biotechnology potential. G protein-coupled receptors (GPCRs), the main targets in drug development, are of major interest in antibody development programs. Metabotropic glutamate receptors are dimeric GPCRs that can control synaptic activity in a multitude of ways. Here we identify llama nanobodies that spec...
Alternative Titles
Full title
Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation
Authors, Artists and Contributors
Author / Creator
Nevoltris, Damien
de Bundel, Dimitri
Bossi, Simon
Moreno-Delgado, David
Rovira, Xavier
Møller, Thor C.
El Moustaine, Driss
Mathieu, Michaël
Blanc, Emilie
McLean, Heather
Dupuis, Elodie
Mathis, Gérard
Trinquet, Eric
Daniel, Hervé
Valjent, Emmanuel
Baty, Daniel
Chames, Patrick
Rondard, Philippe
Pin, Jean-Philippe
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_816648732d614ed3bfb0746f18dd9438
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_816648732d614ed3bfb0746f18dd9438
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01489-1
