Oxidative stress-induced MMP- and γ-secretase-dependent VE-cadherin processing is modulated by the p...
Oxidative stress-induced MMP- and γ-secretase-dependent VE-cadherin processing is modulated by the proteasome and BMP9/10
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Classical cadherins, including vascular endothelial (VE)-cadherin, are targeted by matrix metalloproteinases (MMPs) and γ-secretase during adherens junction (AJ) disassembly, a mechanism that might have relevance for endothelial cell (EC) integrity and vascular homeostasis. Here, we show that oxidative stress triggered by H
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Oxidative stress-induced MMP- and γ-secretase-dependent VE-cadherin processing is modulated by the proteasome and BMP9/10
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TN_cdi_doaj_primary_oai_doaj_org_article_8169a08a0cf84a9b98f50732f4d0ad0e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8169a08a0cf84a9b98f50732f4d0ad0e
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-27308-2