Aneuploidy as a cause of impaired chromatin silencing and mating-type specification in budding yeast
Aneuploidy as a cause of impaired chromatin silencing and mating-type specification in budding yeast
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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Aneuploidy and epigenetic alterations have long been associated with carcinogenesis, but it was unknown whether aneuploidy could disrupt the epigenetic states required for cellular differentiation. In this study, we found that ~3% of random aneuploid karyotypes in yeast disrupt the stable inheritance of silenced chromatin during cell proliferation....
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Aneuploidy as a cause of impaired chromatin silencing and mating-type specification in budding yeast
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TN_cdi_doaj_primary_oai_doaj_org_article_819ebc5faddb4f61b6c2d95607a75abb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_819ebc5faddb4f61b6c2d95607a75abb
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.27991
