Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associat...
Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Heart failure is the major cause of death for muscular dystrophy patients, however, the molecular pathomechanism remains unknown. Here, we show the detailed molecular pathogenesis of muscular dystrophy-associated cardiomyopathy in mice lacking the fukutin gene (
Fktn
), the causative gene for Fukuyama muscular dystrophy. Although cardiac
F...
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Full title
Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure
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TN_cdi_doaj_primary_oai_doaj_org_article_820773bb827b414a804a856b83957e6d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_820773bb827b414a804a856b83957e6d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13623-2
