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Single-cell microglial transcriptomics during demyelination defines a microglial state required for...

Single-cell microglial transcriptomics during demyelination defines a microglial state required for...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_82452501e5814e46b46a90da3e09d6ab

Single-cell microglial transcriptomics during demyelination defines a microglial state required for lytic carcass clearance

About this item

Full title

Single-cell microglial transcriptomics during demyelination defines a microglial state required for lytic carcass clearance

Publisher

England: BioMed Central Ltd

Journal title

Molecular neurodegeneration, 2022-12, Vol.17 (1), p.82-82, Article 82

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Microglia regulate the response to injury and disease in the brain and spinal cord. In white matter diseases microglia may cause demyelination. However, how microglia respond and regulate demyelination is not fully understood.
To understand how microglia respond during demyelination, we fed mice cuprizone-a potent demyelinating agent-and assesse...

Alternative Titles

Full title

Single-cell microglial transcriptomics during demyelination defines a microglial state required for lytic carcass clearance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_82452501e5814e46b46a90da3e09d6ab

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_82452501e5814e46b46a90da3e09d6ab

Other Identifiers

ISSN

1750-1326

E-ISSN

1750-1326

DOI

10.1186/s13024-022-00584-2

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