1158 Evaluation of the potency of antibody drug conjugate-free drugs on innate immune cells
1158 Evaluation of the potency of antibody drug conjugate-free drugs on innate immune cells
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London: BMJ Publishing Group Ltd
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English
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London: BMJ Publishing Group Ltd
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BackgroundAntibody drug conjugates (ADCs), that pair highly cytotoxic drugs with a tumor targeting antibody, have become a mainstay of many cancer treatment paradigms. Currently approved ADCs utilize payloads that disrupt tubulin (including monomethyl auristatins (MMAE and MMAF), inhibit topoisomerase 1 (DXd and SN-38) or induce DNA cleavage (ozoga...
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1158 Evaluation of the potency of antibody drug conjugate-free drugs on innate immune cells
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TN_cdi_doaj_primary_oai_doaj_org_article_8259033f40114af99661152514c72d29
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8259033f40114af99661152514c72d29
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E-ISSN
2051-1426
DOI
10.1136/jitc-2023-SITC2023.1158
