The UFMylation pathway is impaired in Alzheimer’s disease
The UFMylation pathway is impaired in Alzheimer’s disease
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Alzheimer's disease (AD) is characterized by the presence of neurofibrillary tangles made of hyperphosphorylated tau and senile plaques composed of beta-amyloid. These pathognomonic deposits have been implicated in the pathogenesis, although the molecular mechanisms and consequences remain undetermined. UFM1 is an important, but understudied ubiqui...
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Full title
The UFMylation pathway is impaired in Alzheimer’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_825afe7b41d34ac0ab94c874d0893d73
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_825afe7b41d34ac0ab94c874d0893d73
Other Identifiers
ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-024-00784-y
