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Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens th...

Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens th...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_825f4db4af8b457a93e1d6628f784ef4

Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1

About this item

Full title

Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-10, Vol.8 (1), p.790-15, Article 790

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Contractile adherens junctions support cell−cell adhesion, epithelial integrity, and morphogenesis. Much effort has been devoted to understanding how contractility is established; however, less is known about whether contractility can be actively downregulated at junctions nor what function this might serve. We now identify such an inhibitory pathw...

Alternative Titles

Full title

Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_825f4db4af8b457a93e1d6628f784ef4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_825f4db4af8b457a93e1d6628f784ef4

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-00797-w

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