RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization
RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization
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Author / Creator
Alqassim, Emad Y. , Sharma, Shraddha , Khan, A. N. M. Nazmul H. , Emmons, Tiffany R. , Cortes Gomez, Eduardo , Alahmari, Abdulrahman , Singel, Kelly L. , Mark, Jaron , Davidson, Bruce A. , Robert McGray, A. J. , Liu, Qian , Lichty, Brian D. , Moysich, Kirsten B. , Wang, Jianmin , Odunsi, Kunle , Segal, Brahm H. and Baysal, Bora E.
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Pro-inflammatory M1 macrophage polarization is associated with microbicidal and antitumor responses. We recently described APOBEC3A-mediated cytosine-to-uracil (C > U) RNA editing during M1 polarization. However, the functional significance of this editing is unknown. Here we find that APOBEC3A-mediated cellular RNA editing can also be induced by i...
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RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization
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TN_cdi_doaj_primary_oai_doaj_org_article_8289df36f80e4288872e7c05d2e770f3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8289df36f80e4288872e7c05d2e770f3
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-020-01620-x
