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A patterned human primitive heart organoid model generated by pluripotent stem cell self-organizatio...

A patterned human primitive heart organoid model generated by pluripotent stem cell self-organizatio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8291423851734cc79c4f8ca9fb65ced5

A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization

About this item

Full title

A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-12, Vol.14 (1), p.8245-22, Article 8245

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Pluripotent stem cell-derived organoids can recapitulate significant features of organ development in vitro. We hypothesized that creating human heart organoids by mimicking aspects of
in utero
gestation (e.g., addition of metabolic and hormonal factors) would lead to higher physiological and anatomical relevance. We find that heart organoids...

Alternative Titles

Full title

A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8291423851734cc79c4f8ca9fb65ced5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8291423851734cc79c4f8ca9fb65ced5

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-43999-1

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