A patterned human primitive heart organoid model generated by pluripotent stem cell self-organizatio...
A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization
About this item
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Author / Creator
Volmert, Brett , Kiselev, Artem , Juhong, Aniwat , Wang, Fei , Riggs, Ashlin , Kostina, Aleksandra , O’Hern, Colin , Muniyandi, Priyadharshni , Wasserman, Aaron , Huang, Amanda , Lewis-Israeli, Yonatan , Panda, Vishal , Bhattacharya, Sudin , Lauver, Adam , Park, Sangbum , Qiu, Zhen , Zhou, Chao and Aguirre, Aitor
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Pluripotent stem cell-derived organoids can recapitulate significant features of organ development in vitro. We hypothesized that creating human heart organoids by mimicking aspects of
in utero
gestation (e.g., addition of metabolic and hormonal factors) would lead to higher physiological and anatomical relevance. We find that heart organoids...
Alternative Titles
Full title
A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8291423851734cc79c4f8ca9fb65ced5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8291423851734cc79c4f8ca9fb65ced5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-43999-1
