Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies
Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Formation of pathogenic antibodies is a major problem in replacement therapies for inherited protein deficiencies. For example, antibodies to coagulation factors (‘inhibitors’) seriously complicate treatment of haemophilia. While immune tolerance induction (ITI) protocols have been developed, inhibitors against factor IX (FIX) are difficult to erad...
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Full title
Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies
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TN_cdi_doaj_primary_oai_doaj_org_article_82a93c90680c4bf4959b0407338446dc
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_82a93c90680c4bf4959b0407338446dc
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.1002/emmm.201302859
