1522 Revitalizing systemic immune responses in progressive NSCLC using FLT3L and SBRT
1522 Revitalizing systemic immune responses in progressive NSCLC using FLT3L and SBRT
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Author / Creator
Mathew, Divij , Ohri, Nitin , Ngiow, Shin Foong , Wumesh, KC , Halmos, Balazs , Garg, Madhur , Levsky, Jeffrey M , Cheng, Haiying , Gucalp, Rasim , Bodner, William , Kabarriti, Rafi , Gutierrez-Chavez, Claudia , Zakharia, Adel , Kalnicki, Shalom , Yellin, Michael J , Keler, Tibor , Giles, Josephine R , Guha, Chandan and John Wherry, E
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London: BMJ Publishing Group Ltd
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English
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London: BMJ Publishing Group Ltd
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BackgroundFms-like tyrosine kinase 3 ligand (FLT3L) is a potent hematopoietic growth factor that mobilizes stem cells and increases the number of circulating dendritic cells (DCs) in blood and organs. In a murine lung adenocarcinoma model, FLT3L had modest activity as monotherapy but demonstrated synergy when combined with high-dose radiotherapy.1...
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Full title
1522 Revitalizing systemic immune responses in progressive NSCLC using FLT3L and SBRT
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TN_cdi_doaj_primary_oai_doaj_org_article_82d8c6fad55140779770b8cfcd282fbd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_82d8c6fad55140779770b8cfcd282fbd
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E-ISSN
2051-1426
DOI
10.1136/jitc-2023-SITC2023.1522
