Perturbation-based gene regulatory network inference to unravel oncogenic mechanisms
Perturbation-based gene regulatory network inference to unravel oncogenic mechanisms
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The gene regulatory network (GRN) of human cells encodes mechanisms to ensure proper functioning. However, if this GRN is dysregulated, the cell may enter into a disease state such as cancer. Understanding the GRN as a system can therefore help identify novel mechanisms underlying disease, which can lead to new therapies. To deduce regulatory inter...
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Perturbation-based gene regulatory network inference to unravel oncogenic mechanisms
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TN_cdi_doaj_primary_oai_doaj_org_article_82d92cd771e2430780af2d03d54742cb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_82d92cd771e2430780af2d03d54742cb
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-70941-y
