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Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-medi...

Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-medi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83307b9209c64e94a39236b795ab5bf1

Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription

About this item

Full title

Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2021-02, Vol.10

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

The Hippo (Hpo) pathway regulates tissue growth in many animals. Multiple upstream components promote Hpo pathway activity, but the organization of these different inputs, the degree of crosstalk between them, and whether they are regulated in a distinct manner is not well understood. Kibra (Kib) activates the Hpo pathway by recruiting the core Hpo...

Alternative Titles

Full title

Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_83307b9209c64e94a39236b795ab5bf1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83307b9209c64e94a39236b795ab5bf1

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.62326

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