Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-medi...
Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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The Hippo (Hpo) pathway regulates tissue growth in many animals. Multiple upstream components promote Hpo pathway activity, but the organization of these different inputs, the degree of crosstalk between them, and whether they are regulated in a distinct manner is not well understood. Kibra (Kib) activates the Hpo pathway by recruiting the core Hpo...
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Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription
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TN_cdi_doaj_primary_oai_doaj_org_article_83307b9209c64e94a39236b795ab5bf1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83307b9209c64e94a39236b795ab5bf1
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.62326