Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family
Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family
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Author / Creator
Choi, Chulwon , Bae, Jungnam , Kim, Seonghan , Lee, Seho , Kang, Hyunook , Kim, Jinuk , Bang, Injin , Kim, Kiheon , Huh, Won-Ki , Seok, Chaok , Park, Hahnbeom , Im, Wonpil and Choi, Hee-Jung
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Structural and mechanistic studies on human odorant receptors (ORs), key in olfactory signaling, are challenging because of their low surface expression in heterologous cells. The recent structure of OR51E2 bound to propionate provided molecular insight into odorant recognition, but the lack of an inactive OR structure limited understanding of the...
Alternative Titles
Full title
Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_83319c59223f42e0b713a56c562fbed1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83319c59223f42e0b713a56c562fbed1
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-43983-9
