YAP Inhibits the Apoptosis and Migration of Human Rectal Cancer Cells via Suppression of JNK-Drp1-Mi...
YAP Inhibits the Apoptosis and Migration of Human Rectal Cancer Cells via Suppression of JNK-Drp1-Mitochondrial Fission-HtrA2/Omi Pathways
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Author / Creator
Li, Haijun , He, Fucheng , Zhao, Xin , Zhang, Yuan , Chu, Xi , Hua, Chunlan , Qu, Yunhui , Duan, Yu and Ming, Liang
Publisher
Basel, Switzerland: S. Karger AG
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Language
English
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Publisher
Basel, Switzerland: S. Karger AG
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Background/Aims: The Hippo-Yap pathway is associated with tumor development and progression. However, little evidence is available concerning its role in cancer cell apoptosis and migration via mitochondrial homeostasis. Here, we identify mitochondrial fission as a regulator of the Hippo–Yap pathway in human rectal cancer tumorigenesis and metastas...
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Full title
YAP Inhibits the Apoptosis and Migration of Human Rectal Cancer Cells via Suppression of JNK-Drp1-Mitochondrial Fission-HtrA2/Omi Pathways
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TN_cdi_doaj_primary_oai_doaj_org_article_837427af707a491281c607ea457afd97
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_837427af707a491281c607ea457afd97
Other Identifiers
ISSN
1015-8987
E-ISSN
1421-9778
DOI
10.1159/000485946
