Transforming dysfunctional CD8+ T cells into natural controller–like CD8+ T cells: can TCF-1 be the...
Transforming dysfunctional CD8+ T cells into natural controller–like CD8+ T cells: can TCF-1 be the magic wand?
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United States: American Society for Clinical Investigation
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English
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United States: American Society for Clinical Investigation
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HIV infection results in defective CD8+ T cell functions that are incompletely resolved by antiretroviral therapy (ART) except in natural controllers, who have functional CD8+ T cells associated with viral control. In this issue of the JCI, Perdomo-Celis et al. demonstrated that targeting the Wnt/transcription factor T cell factor 1 (Wnt/TCF-1) pat...
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Transforming dysfunctional CD8+ T cells into natural controller–like CD8+ T cells: can TCF-1 be the magic wand?
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TN_cdi_doaj_primary_oai_doaj_org_article_839cc681c2ce4ab6a73fedf0176c8d53
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_839cc681c2ce4ab6a73fedf0176c8d53
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ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI160474
