Harnessing macrophage-drug conjugates for allogeneic cell-based therapy of solid tumors via the TRAI...
Harnessing macrophage-drug conjugates for allogeneic cell-based therapy of solid tumors via the TRAIN mechanism
About this item
Full title
Author / Creator
Taciak, Bartlomiej , Bialasek, Maciej , Kubiak, Malgorzata , Marszalek, Ilona , Gorczak, Malgorzata , Osadchuk, Olha , Kurpiel, Daria , Strzemecki, Damian , Barwik, Karolina , Skorzynski, Marcin , Nowakowska, Julia , Lipiński, Waldemar , Kiraga, Łukasz , Brancewicz, Jan , Klopfleisch, Robert , Krzemiński, Łukasz , Gorka, Emilia , Smolarska, Anna , Padzinska-Pruszynska, Irena , Siemińska, Małgorzata , Guzek, Jakub , Kutner, Jan , Kisiala, Marlena , Wozniak, Krzysztof , Parisi, Giacomo , Piacentini, Roberta , Cassetta, Luca , Forrester, Lesley M. , Bodnar, Lubomir , Weiss, Tobias , Boffi, Alberto , Kucharzewska, Paulina , Rygiel, Tomasz P. and Krol, Magdalena
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Treatment of solid tumors remains challenging and therapeutic strategies require continuous development. Tumor-infiltrating macrophages play a pivotal role in tumor dynamics. Here, we present a Macrophage-Drug Conjugate (MDC) platform technology that enables loading macrophages with ferritin-drug complexes. We first show that macrophages actively t...
Alternative Titles
Full title
Harnessing macrophage-drug conjugates for allogeneic cell-based therapy of solid tumors via the TRAIN mechanism
Authors, Artists and Contributors
Author / Creator
Bialasek, Maciej
Kubiak, Malgorzata
Marszalek, Ilona
Gorczak, Malgorzata
Osadchuk, Olha
Kurpiel, Daria
Strzemecki, Damian
Barwik, Karolina
Skorzynski, Marcin
Nowakowska, Julia
Lipiński, Waldemar
Kiraga, Łukasz
Brancewicz, Jan
Klopfleisch, Robert
Krzemiński, Łukasz
Gorka, Emilia
Smolarska, Anna
Padzinska-Pruszynska, Irena
Siemińska, Małgorzata
Guzek, Jakub
Kutner, Jan
Kisiala, Marlena
Wozniak, Krzysztof
Parisi, Giacomo
Piacentini, Roberta
Cassetta, Luca
Forrester, Lesley M.
Bodnar, Lubomir
Weiss, Tobias
Boffi, Alberto
Kucharzewska, Paulina
Rygiel, Tomasz P.
Krol, Magdalena
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_83a00daf9f684896b6cb93db039be5d4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83a00daf9f684896b6cb93db039be5d4
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-56637-9
