Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular...
Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across clinical conditions
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Author / Creator
Vergauwen, Glenn , Tulkens, Joeri , Pinheiro, Cláudio , Avila Cobos, Francisco , Dedeyne, Sándor , De Scheerder, Marie‐Angélique , Vandekerckhove, Linos , Impens, Francis , Miinalainen, Ilkka , Braems, Geert , Gevaert, Kris , Mestdagh, Pieter , Vandesompele, Jo , Denys, Hannelore , De Wever, Olivier and Hendrix, An
Publisher
United States: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
United States: John Wiley & Sons, Inc
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Scope and Contents
Contents
Separating extracellular vesicles (EV) from blood plasma is challenging and complicates their biological understanding and biomarker development. In this study, we fractionate blood plasma by combining size‐exclusion chromatography (SEC) and OptiPrep density gradient centrifugation to study clinical context‐dependent and time‐dependent variations i...
Alternative Titles
Full title
Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across clinical conditions
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_83a21f9d3adf44778a5e98596e49c8c9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83a21f9d3adf44778a5e98596e49c8c9
Other Identifiers
ISSN
2001-3078
E-ISSN
2001-3078
DOI
10.1002/jev2.12122