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Oleuropein confers neuroprotection against rotenone-induced model of Parkinson’s disease via BDNF/CR...

Oleuropein confers neuroprotection against rotenone-induced model of Parkinson’s disease via BDNF/CR...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83a8c5415f4d459e96e8439d84a5b908

Oleuropein confers neuroprotection against rotenone-induced model of Parkinson’s disease via BDNF/CREB/Akt pathway

About this item

Full title

Oleuropein confers neuroprotection against rotenone-induced model of Parkinson’s disease via BDNF/CREB/Akt pathway

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-02, Vol.13 (1), p.2452-2452, Article 2452

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Major pathological features of Parkinson’s disease (PD) include increase in oxidative stress leading to the aggregation of α-synuclein, mitochondrial dysfunction and apoptosis of dopaminergic neurons. In addition, downregulation of the expression of neurotrophic factors like-Brain Derived Neurotrophic Factor (BDNF) is also involved in PD progressio...

Alternative Titles

Full title

Oleuropein confers neuroprotection against rotenone-induced model of Parkinson’s disease via BDNF/CREB/Akt pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_83a8c5415f4d459e96e8439d84a5b908

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83a8c5415f4d459e96e8439d84a5b908

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-29287-4

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