Repurposing existing medications as cancer therapy: design and feasibility of a randomized pilot inv...
Repurposing existing medications as cancer therapy: design and feasibility of a randomized pilot investigating propranolol administration in patients receiving hematopoietic cell transplantation
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Author / Creator
Knight, Jennifer M. , Kerswill, Stephanie A. , Hari, Parameswaran , Cole, Steve W. , Logan, Brent R. , D’Souza, Anita , Shah, Nirav N. , Horowitz, Mary M. , Stolley, Melinda R. , Sloan, Erica K. , Giles, Karen E. , Costanzo, Erin S. , Hamadani, Mehdi , Chhabra, Saurabh , Dhakal, Binod and Rizzo, J. Douglas
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Repurposing existing medications for antineoplastic purposes can provide a safe, cost-effective, and efficacious means to further augment available cancer care. Clinical and preclinical studies suggest a role for the ß-adrenergic antagonist (ß-blocker) propranolol in reducing rates of tumor progression in both solid and hematologic malignancies. In...
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Full title
Repurposing existing medications as cancer therapy: design and feasibility of a randomized pilot investigating propranolol administration in patients receiving hematopoietic cell transplantation
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_83c55287993342728511687fa8453133
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83c55287993342728511687fa8453133
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-018-4509-0