Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset...
Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The genetic architecture of Parkinson's Disease (PD) is complex and not completely understood. Multiple genetic studies to date have identified multiple causal genes and risk loci. Nevertheless, most of the expected genetic heritability remains unexplained. Polygenic risk scores (PRS) may provide greater statistical power and inform about the genet...
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Full title
Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels
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TN_cdi_doaj_primary_oai_doaj_org_article_83ed4ef373d84b18a45accc46baee481
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83ed4ef373d84b18a45accc46baee481
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ISSN
1471-2377
E-ISSN
1471-2377
DOI
10.1186/s12883-017-0978-z
