A benchmark of algorithms for the analysis of pooled CRISPR screens
A benchmark of algorithms for the analysis of pooled CRISPR screens
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Genome-wide pooled CRISPR-Cas-mediated knockout, activation, and repression screens are powerful tools for functional genomic investigations. Despite their increasing importance, there is currently little guidance on how to design and analyze CRISPR-pooled screens. Here, we provide a review of the commonly used algorithms in the computational analy...
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Full title
A benchmark of algorithms for the analysis of pooled CRISPR screens
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TN_cdi_doaj_primary_oai_doaj_org_article_83f327fae159409aba8562bc507f9781
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83f327fae159409aba8562bc507f9781
Other Identifiers
ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-020-01972-x
