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TALEN based HPV-E7 editing triggers necrotic cell death in cervical cancer cells

TALEN based HPV-E7 editing triggers necrotic cell death in cervical cancer cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83f53160399a4bffbbcca8110f2ae7a9

TALEN based HPV-E7 editing triggers necrotic cell death in cervical cancer cells

About this item

Full title

TALEN based HPV-E7 editing triggers necrotic cell death in cervical cancer cells

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-07, Vol.7 (1), p.5500-12, Article 5500

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Human Papillomavirus E7 and E6 oncoproteins have been considered as suitable candidate anti-viral targets since they cause malignant conversion in cervical cancers. Transcription Activator-Like Effector Nucleases (TALENs) are recent editing tools to knockout genes by inducing double stranded breaks at specific sites in the genome. In here, we have...

Alternative Titles

Full title

TALEN based HPV-E7 editing triggers necrotic cell death in cervical cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_83f53160399a4bffbbcca8110f2ae7a9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83f53160399a4bffbbcca8110f2ae7a9

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-05696-0

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