Multi-mtDNA Variants May Be a Factor Contributing to Mitochondrial Function Variety in the Skin-Deri...
Multi-mtDNA Variants May Be a Factor Contributing to Mitochondrial Function Variety in the Skin-Derived Fibroblasts of Leber's Hereditary Optic Neuropathy Patients
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Author / Creator
Yao, Shun , Zhou, Qingru , Yang, Mingzhu , Li, Ya , Jin, Xiuxiu , Guo, Qingge , Yang, Lin , Qin, Fangyuan and Lei, Bo
Publisher
Lausanne: Frontiers Research Foundation
Journal title
Language
English
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Publication information
Publisher
Lausanne: Frontiers Research Foundation
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Scope and Contents
Contents
Heterogeneity is a major feature of Leber's hereditary optic neuropathy (LHON) and has a significant impact on the manifestation and diagnosis of the disease. This study explored whether multiple variations in mitochondrial genes were associated with the heterogeneity, mainly phenotypic heterogeneity. Ophthalmic examinations were conducted in two p...
Alternative Titles
Full title
Multi-mtDNA Variants May Be a Factor Contributing to Mitochondrial Function Variety in the Skin-Derived Fibroblasts of Leber's Hereditary Optic Neuropathy Patients
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_83f95aea19ad472d9879997e80f8fbda
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_83f95aea19ad472d9879997e80f8fbda
Other Identifiers
ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2022.920221
