Phase 2 study of lenvatinib monotherapy as second-line treatment in unresectable biliary tract cance...
Phase 2 study of lenvatinib monotherapy as second-line treatment in unresectable biliary tract cancer: primary analysis results
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Biliary tract cancer (BTC) has a poor prognosis and lacks a standardized second-line therapy. Vascular endothelial growth factor (VEGF), fibroblast growth factor receptor (FGFR) 4, and platelet-derived growth factor receptor (PDGFR) are highly expressed in BTC. Therefore, lenvatinib (a known inhibitor of VEGF receptors 1-3, FGFRs 1-4, and PDGFR-α)...
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Phase 2 study of lenvatinib monotherapy as second-line treatment in unresectable biliary tract cancer: primary analysis results
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TN_cdi_doaj_primary_oai_doaj_org_article_8403f3bcb9b14a4587ff1a87da4dbffb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8403f3bcb9b14a4587ff1a87da4dbffb
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-020-07365-4