SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic termin...
SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals
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Author / Creator
Andres-Alonso, Maria , Ammar, Mohamed Raafet , Butnaru, Ioana , Gomes, Guilherme M. , Acuña Sanhueza, Gustavo , Raman, Rajeev , Yuanxiang, PingAn , Borgmeyer, Maximilian , Lopez-Rojas, Jeffrey , Raza, Syed Ahsan , Brice, Nicola , Hausrat, Torben J. , Macharadze, Tamar , Diaz-Gonzalez, Silvia , Carlton, Mark , Failla, Antonio Virgilio , Stork, Oliver , Schweizer, Michaela , Gundelfinger, Eckart D. , Kneussel, Matthias , Spilker, Christina , Karpova, Anna and Kreutz, Michael R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Amphisomes are organelles of the autophagy pathway that result from the fusion of autophagosomes with late endosomes. While biogenesis of autophagosomes and late endosomes occurs continuously at axon terminals, non-degradative roles of autophagy at boutons are barely described. Here, we show that in neurons BDNF/TrkB traffick in amphisomes that sig...
Alternative Titles
Full title
SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals
Authors, Artists and Contributors
Author / Creator
Ammar, Mohamed Raafet
Butnaru, Ioana
Gomes, Guilherme M.
Acuña Sanhueza, Gustavo
Raman, Rajeev
Yuanxiang, PingAn
Borgmeyer, Maximilian
Lopez-Rojas, Jeffrey
Raza, Syed Ahsan
Brice, Nicola
Hausrat, Torben J.
Macharadze, Tamar
Diaz-Gonzalez, Silvia
Carlton, Mark
Failla, Antonio Virgilio
Stork, Oliver
Schweizer, Michaela
Gundelfinger, Eckart D.
Kneussel, Matthias
Spilker, Christina
Karpova, Anna
Kreutz, Michael R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8405b7ea05e8461086f8fdd56ee7dec8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8405b7ea05e8461086f8fdd56ee7dec8
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13224-z