EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells
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Author / Creator
Ragazzini, Roberta , Pérez-Palacios, Raquel , Baymaz, Irem H. , Diop, Seynabou , Ancelin, Katia , Zielinski, Dina , Michaud, Audrey , Givelet, Maëlle , Borsos, Mate , Aflaki, Setareh , Legoix, Patricia , Jansen, Pascal W. T. C. , Servant, Nicolas , Torres-Padilla, Maria-Elena , Bourc’his, Deborah , Fouchet, Pierre , Vermeulen, Michiel and Margueron, Raphaël
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The Polycomb group of proteins is required for the proper orchestration of gene expression due to its role in maintaining transcriptional silencing. It is composed of several chromatin modifying complexes, including Polycomb Repressive Complex 2 (PRC2), which deposits H3K27me2/3. Here, we report the identification of a cofactor of PRC2, EZHIP (EZH1...
Alternative Titles
Full title
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells
Authors, Artists and Contributors
Author / Creator
Pérez-Palacios, Raquel
Baymaz, Irem H.
Diop, Seynabou
Ancelin, Katia
Zielinski, Dina
Michaud, Audrey
Givelet, Maëlle
Borsos, Mate
Aflaki, Setareh
Legoix, Patricia
Jansen, Pascal W. T. C.
Servant, Nicolas
Torres-Padilla, Maria-Elena
Bourc’his, Deborah
Fouchet, Pierre
Vermeulen, Michiel
Margueron, Raphaël
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_840ba9a727064edb97ff673ade34b357
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_840ba9a727064edb97ff673ade34b357
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11800-x