Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in heal...
Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease
About this item
Full title
Author / Creator
Moss, Joshua , Magenheim, Judith , Neiman, Daniel , Zemmour, Hai , Loyfer, Netanel , Korach, Amit , Samet, Yaacov , Maoz, Myriam , Druid, Henrik , Arner, Peter , Fu, Keng-Yeh , Kiss, Endre , Spalding, Kirsty L. , Landesberg, Giora , Zick, Aviad , Grinshpun, Albert , Shapiro, A. M. James , Grompe, Markus , Wittenberg, Avigail Dreazan , Glaser, Benjamin , Shemer, Ruth , Kaplan, Tommy and Dor, Yuval
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Methylation patterns of circulating cell-free DNA (cfDNA) contain rich information about recent cell death events in the body. Here, we present an approach for unbiased determination of the tissue origins of cfDNA, using a reference methylation atlas of 25 human tissues and cell types. The method is validated using in silico simulations as well as...
Alternative Titles
Full title
Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease
Authors, Artists and Contributors
Author / Creator
Magenheim, Judith
Neiman, Daniel
Zemmour, Hai
Loyfer, Netanel
Korach, Amit
Samet, Yaacov
Maoz, Myriam
Druid, Henrik
Arner, Peter
Fu, Keng-Yeh
Kiss, Endre
Spalding, Kirsty L.
Landesberg, Giora
Zick, Aviad
Grinshpun, Albert
Shapiro, A. M. James
Grompe, Markus
Wittenberg, Avigail Dreazan
Glaser, Benjamin
Shemer, Ruth
Kaplan, Tommy
Dor, Yuval
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_841a0167145749b69b07423fda860202
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_841a0167145749b69b07423fda860202
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-07466-6
