Nano delivery of simvastatin targets liver sinusoidal endothelial cells to remodel tumor microenviro...
Nano delivery of simvastatin targets liver sinusoidal endothelial cells to remodel tumor microenvironment for hepatocellular carcinoma
About this item
Full title
Author / Creator
Yu, Zhuo , Guo, Jianfeng , Liu, Yun , Wang, Menglin , Liu, Zhengsheng , Gao, Yueqiu and Huang, Leaf
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Hepatocellular carcinoma (HCC) developed in fibrotic liver does not respond well to immunotherapy, mainly due to the stromal microenvironment and the fibrosis-related immunosuppressive factors. The characteristic of liver sinusoidal endothelial cells (LSECs) in contributing to fibrosis and orchestrating immune response is responsible for the refrac...
Alternative Titles
Full title
Nano delivery of simvastatin targets liver sinusoidal endothelial cells to remodel tumor microenvironment for hepatocellular carcinoma
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_841ac7c1c8c94b6287e7f779febfa2a1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_841ac7c1c8c94b6287e7f779febfa2a1
Other Identifiers
ISSN
1477-3155
E-ISSN
1477-3155
DOI
10.1186/s12951-021-01205-8
