Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair
Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair
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Author / Creator
Li, Zhi , Hodgkinson, Tom , Gothard, Elizabeth J. , Boroumand, Soulmaz , Lamb, Rebecca , Cummins, Ian , Narang, Priyanka , Sawtell, Amy , Coles, Jenny , Leonov, German , Reboldi, Andrea , Buckley, Christopher D. , Cupedo, Tom , Siebel, Christian , Bayat, Ardeshir , Coles, Mark C. and Ambler, Carrie A.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Notch has a well-defined role in controlling cell fate decisions in the embryo and the adult epidermis and immune systems, yet emerging evidence suggests Notch also directs non-cell-autonomous signalling in adult tissues. Here, we show that Notch1 works as a damage response signal. Epidermal Notch induces recruitment of immune cell subsets includin...
Alternative Titles
Full title
Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_843bd1d443c040959d4e14ce28f79819
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_843bd1d443c040959d4e14ce28f79819
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms11394
