Targeting the mitochondrial protein YME1L to inhibit osteosarcoma cell growth in vitro and in vivo
Targeting the mitochondrial protein YME1L to inhibit osteosarcoma cell growth in vitro and in vivo
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Author / Creator
Sun, Xu , Shi, Ce , Dai, Jin , Zhang, Mei-Qing , Pei, Dong-Sheng and Yang, Lei
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Exploring novel diagnostic and therapeutic biomarkers is extremely important for osteosarcoma. YME1 Like 1 ATPase (YME1L), locating in the mitochondrial inner membrane, is key in regulating mitochondrial plasticity and metabolic activity. Its expression and potential functions in osteosarcoma are studied in the present study. We show that
YME1L<...
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Full title
Targeting the mitochondrial protein YME1L to inhibit osteosarcoma cell growth in vitro and in vivo
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TN_cdi_doaj_primary_oai_doaj_org_article_8453d78e109f4ceaa5030896869f96d8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8453d78e109f4ceaa5030896869f96d8
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-024-06722-6