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Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic a...

Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_84706af8be0f4cffa61c89d018e75e54

Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic and targetable tissue states

About this item

Full title

Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic and targetable tissue states

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-05, Vol.14 (1), p.2586-2586, Article 2586

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Glioblastoma (GBM) diffusely infiltrates the brain and intermingles with non-neoplastic brain cells, including astrocytes, neurons and microglia/myeloid cells. This complex mixture of cell types forms the biological context for therapeutic response and tumor recurrence. We used single-nucleus RNA sequencing and spatial transcriptomics to determine...

Alternative Titles

Full title

Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic and targetable tissue states

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_84706af8be0f4cffa61c89d018e75e54

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_84706af8be0f4cffa61c89d018e75e54

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-38186-1

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