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A TLR7/8 agonist increases efficacy of anti-fentanyl vaccines in rodent and porcine models

A TLR7/8 agonist increases efficacy of anti-fentanyl vaccines in rodent and porcine models

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_84711b1689474c11879e5e0dec9e620c

A TLR7/8 agonist increases efficacy of anti-fentanyl vaccines in rodent and porcine models

About this item

Full title

A TLR7/8 agonist increases efficacy of anti-fentanyl vaccines in rodent and porcine models

Publisher

London: Nature Publishing Group UK

Journal title

npj vaccines, 2023-07, Vol.8 (1), p.107-17, Article 107

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Opioid use disorders (OUD) and overdose are public health threats worldwide. Widespread access to highly potent illicit synthetic opioids such as fentanyl is driving the recent rise in fatal overdoses. Vaccines containing fentanyl-based haptens conjugated to immunogenic carrier proteins offer a long-lasting, safe, and cost-effective strategy to pro...

Alternative Titles

Full title

A TLR7/8 agonist increases efficacy of anti-fentanyl vaccines in rodent and porcine models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_84711b1689474c11879e5e0dec9e620c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_84711b1689474c11879e5e0dec9e620c

Other Identifiers

ISSN

2059-0105

E-ISSN

2059-0105

DOI

10.1038/s41541-023-00697-9

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