C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers
C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers
About this item
Full title
Author / Creator
Nanaura, Hitoki , Kawamukai, Honoka , Fujiwara, Ayano , Uehara, Takeru , Aiba, Yuichiro , Nakanishi, Mari , Shiota, Tomo , Hibino, Masaki , Wiriyasermkul, Pattama , Kikuchi, Sotaro , Nagata, Riko , Matsubayashi, Masaya , Shinkai, Yoichi , Niwa, Tatsuya , Mannen, Taro , Morikawa, Naritaka , Iguchi, Naohiko , Kiriyama, Takao , Morishima, Ken , Inoue, Rintaro , Sugiyama, Masaaki , Oda, Takashi , Kodera, Noriyuki , Toma-Fukai, Sachiko , Sato, Mamoru , Taguchi, Hideki , Nagamori, Shushi , Shoji, Osami , Ishimori, Koichiro , Matsumura, Hiroyoshi , Sugie, Kazuma , Saio, Tomohide , Yoshizawa, Takuya and Mori, Eiichiro
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Nuclear import receptors (NIRs) not only transport RNA-binding proteins (RBPs) but also modify phase transitions of RBPs by recognizing nuclear localization signals (NLSs). Toxic arginine-rich poly-dipeptides from
C9orf72
interact with NIRs and cause nucleocytoplasmic transport deficit. However, the molecular basis for the toxicity of arginin...
Alternative Titles
Full title
C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers
Authors, Artists and Contributors
Author / Creator
Kawamukai, Honoka
Fujiwara, Ayano
Uehara, Takeru
Aiba, Yuichiro
Nakanishi, Mari
Shiota, Tomo
Hibino, Masaki
Wiriyasermkul, Pattama
Kikuchi, Sotaro
Nagata, Riko
Matsubayashi, Masaya
Shinkai, Yoichi
Niwa, Tatsuya
Mannen, Taro
Morikawa, Naritaka
Iguchi, Naohiko
Kiriyama, Takao
Morishima, Ken
Inoue, Rintaro
Sugiyama, Masaaki
Oda, Takashi
Kodera, Noriyuki
Toma-Fukai, Sachiko
Sato, Mamoru
Taguchi, Hideki
Nagamori, Shushi
Shoji, Osami
Ishimori, Koichiro
Matsumura, Hiroyoshi
Sugie, Kazuma
Saio, Tomohide
Yoshizawa, Takuya
Mori, Eiichiro
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_84769c6bce8f47bf9553e2e7438eb8a6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_84769c6bce8f47bf9553e2e7438eb8a6
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25560-0
