Tumor-Educated Platelets and Angiogenesis in Glioblastoma: Another Brick in the Wall for Novel Progn...
Tumor-Educated Platelets and Angiogenesis in Glioblastoma: Another Brick in the Wall for Novel Prognostic and Targetable Biomarkers, Changing the Vision from a Localized Tumor to a Systemic Pathology
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Author / Creator
Campanella, Rolando , Guarnaccia, Laura , Cordiglieri, Chiara , Trombetta, Elena , Caroli, Manuela , Carrabba, Giorgio , La Verde, Nicla , Rampini, Paolo , Gaudino, Chiara , Costa, Antonella , Luzzi, Sabino , Mantovani, Giovanna , Locatelli, Marco , Riboni, Laura , Navone, Stefania Elena and Marfia, Giovanni
Publisher
Switzerland: MDPI
Journal title
Language
English
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Publisher
Switzerland: MDPI
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Contents
Circulating platelets (PLTs) are able to affect glioblastoma (GBM) microenvironment by supplying oncopromoter and pro-angiogenic factors. Among these mediators, sphingosine-1-phophate (S1P) has emerged as a potent bioactive lipid enhancing cell proliferation and survival. Here, we investigated the effect of "tumor education", characterizing PLTs fr...
Alternative Titles
Full title
Tumor-Educated Platelets and Angiogenesis in Glioblastoma: Another Brick in the Wall for Novel Prognostic and Targetable Biomarkers, Changing the Vision from a Localized Tumor to a Systemic Pathology
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TN_cdi_doaj_primary_oai_doaj_org_article_847eeeb8300a4993b2f9b0cb3fcd2357
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_847eeeb8300a4993b2f9b0cb3fcd2357
Other Identifiers
ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells9020294
