Prion-induced photoreceptor degeneration begins with misfolded prion protein accumulation in cones a...
Prion-induced photoreceptor degeneration begins with misfolded prion protein accumulation in cones at two distinct sites: cilia and ribbon synapses
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England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Accumulation of misfolded host proteins is central to neuropathogenesis of numerous human brain diseases including prion and prion-like diseases. Neurons of retina are also affected by these diseases. Previously, our group and others found that prion-induced retinal damage to photoreceptor cells in mice and humans resembled pathology of human retin...
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Prion-induced photoreceptor degeneration begins with misfolded prion protein accumulation in cones at two distinct sites: cilia and ribbon synapses
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TN_cdi_doaj_primary_oai_doaj_org_article_84a6bced1441416fb121b7d946b40211
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_84a6bced1441416fb121b7d946b40211
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-021-01120-x
