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Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of...

Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_84ab9aaf43bd41779abbb7561b6c18e0

Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms

About this item

Full title

Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms

Publisher

London: Nature Publishing Group UK

Journal title

Communications biology, 2023-03, Vol.6 (1), p.295-295, Article 295

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Prolactin (PRL) is elevated in B-cell-mediated lymphoproliferative diseases and promotes B-cell survival. Whether PRL or PRL receptors drive the evolution of B-cell malignancies is unknown. We measure changes in B cells after knocking down the pro-proliferative, anti-apoptotic long isoform of the PRL receptor (LFPRLR) in vivo in systemic lupus eryt...

Alternative Titles

Full title

Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_84ab9aaf43bd41779abbb7561b6c18e0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_84ab9aaf43bd41779abbb7561b6c18e0

Other Identifiers

ISSN

2399-3642

E-ISSN

2399-3642

DOI

10.1038/s42003-023-04667-8

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