Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing pept...
Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway
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Author / Creator
Yang, Yang , Wang, Qi , Song, Dongjian , Zen, Ruirui , Zhang, Lei , Wang, Yingjun , Yang, Heying , Zhang, Da , Jia, Jia , Zhang, Jiao and Wang, Jiaxiang
Publisher
London: BioMed Central Ltd
Journal title
Language
English
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Publisher
London: BioMed Central Ltd
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Contents
Background Autophagy is an intracellular process through which intracellular components are recycled in response to nutrient or growth factor deficiency to maintain homeostasis. We identified the peptide autophagy-related cancer-suppressing peptide (ARCSP), a potential antitumor peptide that disrupts intracellular homeostasis by blocking autophagic...
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Full title
Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_84af4f869eba4c0882a3cd58d7b01c3c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_84af4f869eba4c0882a3cd58d7b01c3c
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-020-01701-z
