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Genome-Wide Methylation Changes Associated with Replicative Senescence and Differentiation in Endoth...

Genome-Wide Methylation Changes Associated with Replicative Senescence and Differentiation in Endoth...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_85203422a25f4eee9382661ce88f6dab

Genome-Wide Methylation Changes Associated with Replicative Senescence and Differentiation in Endothelial and Bone Marrow Mesenchymal Stromal Cells

About this item

Full title

Genome-Wide Methylation Changes Associated with Replicative Senescence and Differentiation in Endothelial and Bone Marrow Mesenchymal Stromal Cells

Publisher

Switzerland: MDPI AG

Journal title

Cells (Basel, Switzerland), 2023-01, Vol.12 (2), p.285

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Bone marrow mesenchymal stromal cells (BMSCs) are multipotent cells able to self-renew and differentiate, depending on the microenvironment, into adipocytes and osteoblasts. These cells have a limited number of replications and enter replicative senescence during in vitro expansion. The role of DNA methylation (DNAm) assumes importance in cell func...

Alternative Titles

Full title

Genome-Wide Methylation Changes Associated with Replicative Senescence and Differentiation in Endothelial and Bone Marrow Mesenchymal Stromal Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_85203422a25f4eee9382661ce88f6dab

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_85203422a25f4eee9382661ce88f6dab

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells12020285

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