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Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus

Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_85323af00c3940d4aadf6ca47ac55360

Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus

About this item

Full title

Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-04, Vol.11 (1), p.7893-12, Article 7893

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

APOBEC3 (A3) enzymes are best known for their role as antiviral restriction factors and as mutagens in cancer. Although four of them, A3A, A3B, A3F and A3G, are induced by type-1-interferon (IFN-I), their role in inflammatory conditions is unknown. We thus investigated the expression of
A3
, and particularly
A3A
and
A3B
because of...

Alternative Titles

Full title

Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_85323af00c3940d4aadf6ca47ac55360

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_85323af00c3940d4aadf6ca47ac55360

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-87024-1

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