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Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer

Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8561db064eef44aab4d075c66cf8b992

Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer

About this item

Full title

Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-12, Vol.15 (1), p.10534-20, Article 10534

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Fibroblast heterogeneity is increasingly recognised across cancer conditions. Given their important contribution to disease progression, mapping fibroblasts’ heterogeneity is critical to devise effective anti-cancer therapies. Cancer-associated fibroblasts (CAFs) represent the most abundant cell population in pancreatic ductal adenocarcinoma (PDAC)...

Alternative Titles

Full title

Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8561db064eef44aab4d075c66cf8b992

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8561db064eef44aab4d075c66cf8b992

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-54975-8

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