Mitochondrial genome and its regulator TFAM modulates head and neck tumourigenesis through intracell...
Mitochondrial genome and its regulator TFAM modulates head and neck tumourigenesis through intracellular metabolic reprogramming and activation of oncogenic effectors
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Mitochondrial transcriptional factor A (TFAM) acts as a key regulatory to control mitochondrial DNA (mtDNA); the impact of TFAM and mtDNA in modulating carcinogenesis is controversial. Current study aims to define TFAM mediated regulations in head and neck cancer (HNC). Multifaceted analyses in HNC cells genetically manipulated for TFAM were perfor...
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Mitochondrial genome and its regulator TFAM modulates head and neck tumourigenesis through intracellular metabolic reprogramming and activation of oncogenic effectors
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TN_cdi_doaj_primary_oai_doaj_org_article_8562c13e011d4bec892199db3a74719c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8562c13e011d4bec892199db3a74719c
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-021-04255-w
