Cellular senescence: a key therapeutic target in aging and diseases
Cellular senescence: a key therapeutic target in aging and diseases
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Cellular senescence is a hallmark of aging defined by stable exit from the cell cycle in response to cellular damage and stress. Senescent cells (SnCs) can develop a characteristic pathogenic senescence-associated secretory phenotype (SASP) that drives secondary senescence and disrupts tissue homeostasis, resulting in loss of tissue repair and rege...
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Full title
Cellular senescence: a key therapeutic target in aging and diseases
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TN_cdi_doaj_primary_oai_doaj_org_article_85d40b74e6c34ce2a01a1f9d5815c6bd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_85d40b74e6c34ce2a01a1f9d5815c6bd
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI158450
