Trophoblast-derived miR-410-5p induces M2 macrophage polarization and mediates immunotolerance at th...
Trophoblast-derived miR-410-5p induces M2 macrophage polarization and mediates immunotolerance at the fetal-maternal interface by targeting the STAT1 signaling pathway
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Author / Creator
Yang, Jing , Li, Longfei , Wang, Linlin , Chen, Ruizhi , Yang, Xiaobing , Wu, Juanhua , Feng, Gang , Ding, Jinli , Diao, Lianghui , Chen, Jiao and Yang, Jing
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Macrophages phenotypic deviation and immune imbalance play vital roles in pregnancy-associated diseases such as spontaneous miscarriage. Trophoblasts regulate phenotypic changes in macrophages, however, their underlying mechanism during pregnancy remains unclear. Therefore, this study aimed to elucidate the potential function of trophoblast-derived...
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Full title
Trophoblast-derived miR-410-5p induces M2 macrophage polarization and mediates immunotolerance at the fetal-maternal interface by targeting the STAT1 signaling pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_85e310a9482d4228ac0b0e5ec2d0a40a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_85e310a9482d4228ac0b0e5ec2d0a40a
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ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-023-04831-y